Buying guide 8 min read

GHK‑Cu (copper peptide): what it is, how it is supplied, and how to choose a research supplier

GHK-Cu vial — lyophilized, OXpeptides label

In the catalog

GHK‑Cu

from $35

Purity spec >99% by HPLC

SizePricePer mg
50 mg$35$0.70/mg
100 mg$45$0.45/mg

Research use only. Not for human or veterinary use. Availability is on the product page.

GHK‑Cu is the tripeptide glycyl-L-histidyl-L-lysine complexed with a copper(II) ion, supplied as a blue-violet lyophilized powder in sealed glass vials of 100, 200 or 300 mg for laboratory research. Research-grade GHK‑Cu is bought from a supplier that publishes a batch-specific certificate of analysis (HPLC purity and mass confirmation) from an independent laboratory, ships from EU stock, and sells it as a reagent — not as a cosmetic and not for any personal use.

Written by the OXpeptides editorial teamLast updated 16 September 2026
This guide describes a research reagent as a product: composition, formats, purity documentation and storage. It is not usage information. Research use only. Not for human or veterinary use.

What GHK‑Cu is

GHK‑Cu is a small peptide of three amino acids — glycine, histidine and lysine (Gly-His-Lys) — bound to one copper(II) ion.

The free tripeptide (GHK) has a molecular weight of about 340 Da; the copper complex is about 404 Da. It was first described by Loren Pickart in 1973 and is the most studied of the so-called copper peptides.

Two things make it easy to recognize on a laboratory bench:

  • The color. The copper(II) ion gives the lyophilized powder a blue-to-violet tint. A white or gray "GHK‑Cu" powder is either the copper-free tripeptide or something else entirely.
  • The mass. On a certificate of analysis, mass spectrometry confirms the peptide at the expected molecular weight; the copper content is sometimes reported separately.

In the catalog, GHK‑Cu is sold as a research reagent: a sealed vial of lyophilized powder with its Janoshik analysis report per size once published.

It is not a serum, not a cream, and not a product for personal use. Research use only. Not for human or veterinary use.

GHK copper peptide, GHK‑Cu, copper tripeptide: one molecule, three names

Searches for "GHK copper peptide", "GHK Cu", "GHK‑Cu" and "copper tripeptide" all point to the same compound: the tripeptide GHK carrying one copper(II) ion.

Suppliers and papers write it differently; the certificate of analysis settles it with the mass. Two labels do describe different objects:

  • GHK (no copper) — the free tripeptide, a white powder of about 340 Da. Some listings sell this and call it "copper peptide"; the COA mass tells them apart.
  • GHK‑Cu — the copper complex, blue-violet, about 404 Da. This is what the catalog lists.

When a listing says "GHK copper peptide" without a mass on the COA, ask which of the two it is.

"Copper peptide" on Amazon vs GHK‑Cu as a reagent

Most of what Google returns for "copper peptide" is cosmetics: serums and creams that contain GHK‑Cu at a fraction of a percent, mixed with water, glycerin and preservatives.

That is a different object from what a laboratory orders.

What you are looking atCosmetic serumResearch reagent
FormLiquid, mixed formulaLyophilized powder, single compound
Quantity of GHK‑CuRarely stated, typically < 1 %Stated in mg on the label (100, 200, 300 mg)
Purity documentationNoneBatch COA: HPLC purity, mass confirmation
ContainerDropper or pump bottleSealed glass vial, crimp cap, printed label
StorageRoom temperatureFreezer, protected from light and moisture
Intended purposeConsumer productLaboratory research only

If a listing calls itself "GHK‑Cu" but gives no mg quantity, no lot number and no COA, it is a cosmetic or a reseller — not a research supply.

GHK-Cu 100 mg — sealed lyophilized vial, GHK-Cu label
GHK-Cu as it ships : one sealed vial of lyophilized powder, 100 mg on the label.

How GHK‑Cu is supplied: sizes and what is in the vial

Research GHK‑Cu comes as a lyophilized (freeze-dried) powder in a glass vial closed with a rubber septum and an aluminum crimp cap. The label states the compound, the net quantity in milligrams and the words "research use only".

The catalog offers three sizes — 100 mg, 200 mg and 300 mg — and the price per milligram is listed for each.

The live table at the top of this page is read directly from the catalog, so the prices shown there are the prices in force today. See GHK‑Cu in the catalog for availability.

What "100 mg" means on the label

The number is the net mass of GHK‑Cu powder in the vial, as filled, and it is the quantity the certificate of analysis refers to.

The vial itself is over-sized (typically 3 mL for 100 mg): the powder occupies only the bottom. That is normal for lyophilized material and is not a short fill.

Why the powder can look like a cake, a film or loose crystals

Freeze-drying leaves the peptide as a porous cake. During shipping the cake can break into a film on the glass or into loose blue-violet particles. The appearance does not change the quantity or the purity; only the COA does.

What the certificate of analysis must show

The COA is the document that turns a vial of blue powder into a defined reagent. For GHK‑Cu, a usable certificate carries:

  • The laboratory's name and a verifiable identifier. Independent labs (Janoshik is the reference for this market) give each test a number that anyone can look up on the lab's site. A COA that cannot be looked up is a PDF, not a certificate.
  • The lot number — with the task number and verification key the laboratory confirms.
  • HPLC purity as a measured percentage (for example 99.2 %), with the chromatogram. "≥ 98 %" printed without a chromatogram is a claim, not a measurement.
  • Mass confirmation by mass spectrometry: the observed mass matches GHK‑Cu.
  • The date of the test. A certificate older than a few months describes a lot that has probably sold through.
  • A photograph of the tested vial wearing the supplier's own label. A COA showing an unlabeled vial was issued to someone else — usually the manufacturer — and says nothing about what this supplier bottled.

The full checklist, with examples of what a doctored certificate looks like, is in how to read a peptide COA.

Certificate of analysisbatch-specific1Product & sequencethe compound, spelled out2Lot numbermatches the report at the laboratory3Purity (HPLC)main peak ÷ all peaks, in %4Identity (MS)measured mass vs expected5Method & columnhow the run was done6Date · laboratorywho tested, and when
The six fields a batch COA must carry, in the order a reader checks them. A certificate that skips the lot number or the mass confirmation describes a compound, not the vial in hand.

Storage of the sealed vial

GHK‑Cu is stable as a lyophilized powder when it is kept cold, dark and dry. The catalog's storage line for the sealed vial:

  • Temperature: −20 °C for long-term storage; a refrigerator (2–8 °C) is acceptable for short periods.
  • Light: keep the vial in its box or in an opaque container. The copper complex is light-sensitive.
  • Moisture: the powder is hygroscopic. Let a cold vial reach room temperature before removing it from its bag, so no condensation forms on the glass.
  • Shelf life: 24 months from the fill date for a sealed vial stored as above.

Shipping at ambient temperature for a few days does not degrade the sealed powder; that is why research peptides ship without cold packs. The general rules, size by size, are in lyophilized peptides: storage and shelf life.

Freezer−20 °C · yearsFridge2–8 °C · monthsIn transitambient · daysKeep the sealed vial away fromheatlightmoistureair
The sealed vial, three places : the freezer for the long term, the fridge for the short term, the parcel for a few days. The stopper stays on ; the four things that degrade a lyophilized powder stay out.

How to choose a GHK‑Cu supplier in Europe

"Buy GHK‑Cu" returns a mix of cosmetic brands, clinics and research suppliers. To sort them, ask six questions of the product page — not of the marketing.

  1. Is there a batch COA from a named independent lab, and can it be verified on the lab's site? No verifiable COA = no purchase.
  2. Does the COA show the supplier's own label? A manufacturer's certificate, re-used by a reseller, does not cover what was re-bottled or re-labeled.
  3. Is the quantity stated in mg, with a certificate for the lot?
  4. Does the supplier ship from EU stock, tracked, in a few days? A parcel from outside the European Union goes through customs and can sit there for weeks.
  5. Does the page describe the product only — composition, purity, storage — with "research use only" stated plainly? A supplier that publishes usage content is a supplier that is easy to shut down; that risk becomes yours when your order is in transit.
  6. Is the price at or above the market, not far below it? Third-party testing costs several hundred dollars per lot. A price far under the market is a price that did not pay for testing.

The wider checklist (payment, packaging, what to do if a parcel is stopped) is in where to buy research peptides in Europe. The two copper tripeptides are compared line by line in GHK‑Cu vs AHK‑Cu.

GHK‑Cu vs AHK‑Cu

AHK‑Cu is the other copper tripeptide in the catalog (alanine instead of glycine at the N-terminus). It is supplied in smaller sizes (50, 100, 150 mg) and has a thinner literature. Both are described in the AHK‑Cu buying guide.

Price: what the catalog offers

The price of research GHK‑Cu depends on three things: the size of the vial, whether a third-party test was paid for the lot, and where it ships from.

The catalog table at the top of this page shows the current price per vial and per milligram for each size.

What the price includes at OXpeptides: a sealed, labeled vial and its Janoshik analysis report (100 mg published). Ships from the EU · tracked: €9.90, free from €120.

See GHK‑Cu in the catalog →

Published research

The publications a researcher will find when looking this compound up, with their DOI. They characterize the molecule and the models it was studied in; they are listed as references, not as claims about this product.

  1. Pickart L, Margolina A (2018). International Journal of Molecular Sciences, 19(7), 1987.

    doi:10.3390/ijms19071987

    The review most often cited for GHK-Cu: the chemistry of the copper complex, its discovery in 1973, and the gene-expression datasets obtained in cell models.

  2. Campbell JD, McDonough JE, Zeskind JE, et al. (2012). Genome Medicine, 4(8), 67.

    doi:10.1186/gm367

    The Broad Institute Connectivity Map analysis in which GHK was identified; the source of the frequently quoted "4,000 genes" figure, measured in cultured cell lines.

FAQ

Where can I buy GHK‑Cu for research?
From a research-peptide supplier that sells lyophilized GHK‑Cu in labeled vials with a batch-specific, verifiable certificate of analysis. OXpeptides lists GHK‑Cu in 100, 200 and 300 mg vials; the Janoshik report of the 100 mg (task 217016) is published on the product page, the other sizes are in progress. Research use only. Not for human or veterinary use.
What does research-grade GHK‑Cu cost?
Price is set per vial, for each of the three sizes. The live table on this page is read from the catalog and shows the price per milligram for each size. A price far below the market usually means the lot was never tested by a third party.
Why is GHK‑Cu powder blue?
The copper(II) ion in the complex gives the lyophilized powder a blue-to-violet tint. A white "GHK‑Cu" powder is either copper-free GHK or a different compound.
How is GHK‑Cu stored before opening?
Sealed vials are stored at −20 °C, protected from light and moisture; a refrigerator is acceptable for short periods. Shelf life is 24 months for a sealed vial. Ambient shipping for a few days does not degrade the powder.
What should the COA for GHK‑Cu show?
A named independent laboratory with a verifiable test number, the lot number of the certificate, an HPLC purity percentage with the chromatogram, mass-spectrometry confirmation of the compound, the test date, and a photo of the tested vial wearing the supplier's label.

Related guides

Next step

GHK‑Cu in the OXpeptides catalog

Sizes, price per vial, the Janoshik report (once published) and current availability are on the product page.

See GHK‑Cu in the catalog

Research use only. Not for human or veterinary use.